@article{fichtinger2019e,

title = {Toward predictive modeling of catheter‐based pulmonary valve replacement into native right ventricular outflow tracts},

author = {Matthew A Jolley and Andras Lasso and Hannah H Nam and Patrick V Dinh and Adam B Scanlan and Alex V Nguyen and Anna Ilina and Brian Morray and Andrew C Glatz and Francis X McGowan and Kevin Whitehead and Yoav Dori and Joseph H Gorman III and Robert C Gorman and Gabor Fichtinger and Matthew J Gillespie},

url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/ccd.27962},

year  = {2019},

date = {2019-01-01},

journal = {Catheterization and Cardiovascular Interventions},

volume = {93},

issue = {3},

pages = {E143-E152},

publisher = {John Wiley & Sons, Inc.},

abstract = {Background 

Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF) leading to late morbidity and mortality. Transcatheter native outflow tract pulmonary valve replacement has become a reality. However, predicting a secure, atraumatic implantation of a catheter‐based device remains a significant challenge due to the complex and dynamic nature of the right ventricular outflow tract (RVOT). We sought to quantify the differences in compression and volume for actual implants, and those predicted by pre‐implant modeling. 

Methods 

We used custom software to interactively place virtual transcatheter pulmonary valves (TPVs) into RVOT models created from pre‐implant and post Harmony valve implant CT scans of 5 ovine surgical models of TOF to quantify and visualize device volume and compression. 

Results 

Virtual device placement visually mimicked actual device …},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{doi:10.1002/ccd.27962,

title = {Toward predictive modeling of catheter-based pulmonary valve replacement into native right ventricular outflow tracts},

author = {MatthewA Jolley and Andras Lasso and HannahH Nam and Patrick V. Dinh and Adam B. Scanlan and Alexander V. Nguyen and Anna Ilina and Brian Morray and Andrew C. Glatz and FrancisX McGowan and Kevin Whitehead and Yoav Dori and Robert C. Gorman and Robert C. Gorman and Gabor Fichtinger and Matthew J. Gillespie},

url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/ccd.27962},

doi = {10.1002/ccd.27962},

year  = {2018},

date = {2018-11-01},

urldate = {2018-11-01},

journal = {Catheterization and Cardiovascular Interventions},

abstract = {<p>Abstract Background Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF) leading to late morbidity and mortality. Transcatheter native outflow tract pulmonary valve replacement has become a reality. However, predicting a secure, atraumatic implantation of a catheter-based device remains a significant challenge due to the complex and dynamic nature of the right ventricular outflow tract (RVOT). We sought to quantify the differences in compression and volume for actual implants, and those predicted by pre-implant modeling. Methods We used custom software to interactively place virtual transcatheter pulmonary valves (TPVs) into RVOT models created from pre-implant and post Harmony valve implant CT scans of 5 ovine surgical models of TOF to quantify and visualize device volume and compression. Results Virtual device placement visually mimicked actual device placement and allowed for quantification of device volume and radius. On average, simulated proximal and distal device volumes and compression did not vary statistically throughout the cardiac cycle (P = 0.11) but assessment was limited by small sample size. In comparison to actual implants, there was no significant pairwise difference in the proximal third of the device (P > 0.80), but the simulated distal device volume was significantly underestimated relative to actual device implant volume (P = 0.06). Conclusions This study demonstrates that pre-implant modeling which assumes a rigid vessel wall may not accurately predict the degree of distal RVOT expansion following actual device placement. We suggest the potential for virtual modeling of TPVR to be a useful adjunct to procedural planning, but further development is needed.</p>},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{fichtinger2018b,

title = {Comparison of 3D echocardiogram-derived 3D printed valve models to molded models for simulated repair of pediatric atrioventricular valves},

author = {Adam B Scanlan and Alex V Nguyen and Anna Ilina and Andras Lasso and Linnea Cripe and Anusha Jegatheeswaran and Elizabeth Silvestro and Francis X McGowan and Christopher E Mascio and Stephanie Fuller and Thomas L Spray and Meryl S Cohen and Gabor Fichtinger and Matthew A Jolley},

url = {https://link.springer.com/article/10.1007/s00246-017-1785-4},

year  = {2018},

date = {2018-01-01},

journal = {Pediatric cardiology},

volume = {39},

pages = {538-547},

publisher = {Springer US},

abstract = {Mastering the technical skills required to perform pediatric cardiac valve surgery is challenging in part due to limited opportunity for practice. Transformation of 3D echocardiographic (echo) images of congenitally abnormal heart valves to realistic physical models could allow patient-specific simulation of surgical valve repair. We compared materials, processes, and costs for 3D printing and molding of patient-specific models for visualization and surgical simulation of congenitally abnormal heart valves. Pediatric atrioventricular valves (mitral, tricuspid, and common atrioventricular valve) were modeled from transthoracic 3D echo images using semi-automated methods implemented as custom modules in 3D Slicer. Valve models were then both 3D printed in soft materials and molded in silicone using 3D printed “negative” molds. Using pre-defined assessment criteria, valve models were evaluated by …},

keywords = {},

pubstate = {published},

tppubtype = {article}

}